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Detection of significant antiviral drug effects on COVID-19 with reasonable sample sizes in randomized controlled trials: A modeling study
BACKGROUND: Development of an effective antiviral drug for Coronavirus Disease 2019 (COVID-19) is a global health priority. Although several candidate drugs have been identified through in vitro and in vivo models, consistent and compelling evidence from clinical studies is limited. The lack of evid...
Autores principales: | Iwanami, Shoya, Ejima, Keisuke, Kim, Kwang Su, Noshita, Koji, Fujita, Yasuhisa, Miyazaki, Taiga, Kohno, Shigeru, Miyazaki, Yoshitsugu, Morimoto, Shimpei, Nakaoka, Shinji, Koizumi, Yoshiki, Asai, Yusuke, Aihara, Kazuyuki, Watashi, Koichi, Thompson, Robin N., Shibuya, Kenji, Fujiu, Katsuhito, Perelson, Alan S., Iwami, Shingo, Wakita, Takaji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259968/ https://www.ncbi.nlm.nih.gov/pubmed/34228712 http://dx.doi.org/10.1371/journal.pmed.1003660 |
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