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Computation of condition-dependent proteome allocation reveals variability in the macro and micro nutrient requirements for growth

Sustaining a robust metabolic network requires a balanced and fully functioning proteome. In addition to amino acids, many enzymes require cofactors (coenzymes and engrafted prosthetic groups) to function properly. Extensively validated resource allocation models, such as genome-scale models of meta...

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Detalles Bibliográficos
Autores principales: Lloyd, Colton J., Monk, Jonathan, Yang, Laurence, Ebrahim, Ali, Palsson, Bernhard O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259983/
https://www.ncbi.nlm.nih.gov/pubmed/34161321
http://dx.doi.org/10.1371/journal.pcbi.1007817