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Computation of condition-dependent proteome allocation reveals variability in the macro and micro nutrient requirements for growth
Sustaining a robust metabolic network requires a balanced and fully functioning proteome. In addition to amino acids, many enzymes require cofactors (coenzymes and engrafted prosthetic groups) to function properly. Extensively validated resource allocation models, such as genome-scale models of meta...
Autores principales: | Lloyd, Colton J., Monk, Jonathan, Yang, Laurence, Ebrahim, Ali, Palsson, Bernhard O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259983/ https://www.ncbi.nlm.nih.gov/pubmed/34161321 http://dx.doi.org/10.1371/journal.pcbi.1007817 |
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