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Transgenerational inheritance of centromere identity requires the CENP-A N-terminal tail in the C. elegans maternal germ line

Centromere protein A (CENP-A) is a histone H3 variant that defines centromeric chromatin and is essential for centromere function. In most eukaryotes, CENP-A-containing chromatin is epigenetically maintained, and centromere identity is inherited from one cell cycle to the next. In the germ line of t...

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Detalles Bibliográficos
Autores principales: Prosée, Reinier F., Wenda, Joanna M., Özdemir, Isa, Gabus, Caroline, Delaney, Kamila, Schwager, Francoise, Gotta, Monica, Steiner, Florian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259991/
https://www.ncbi.nlm.nih.gov/pubmed/34228701
http://dx.doi.org/10.1371/journal.pbio.3000968