Formulation, characterization, optimization, and in-vivo performance of febuxostat self-nano-emulsifying system loaded sublingual films

Febuxostat (FXS) is a potent antigout drug with poor water solubility and relative high first-pass effect leading to moderate oral bioavailability (<49%). This study aimed to increase FXS solubility and bioavailability by optimizing sublingual fast-dissolving films (SFs) containing a selected FXS...

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Detalles Bibliográficos
Autores principales: Habib, Basant A., Abd El-Samiae, Amina S., El-Houssieny, Boushra M., Tag, Randa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260042/
https://www.ncbi.nlm.nih.gov/pubmed/34176376
http://dx.doi.org/10.1080/10717544.2021.1927247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260042/
https://www.ncbi.nlm.nih.gov/pubmed/34176376
http://dx.doi.org/10.1080/10717544.2021.1927247

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