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Elucidating the Molecular Basis of Sorafenib Resistance in HCC: Current Findings and Future Directions

Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related mortality worldwide. Sorafenib is the first multi-tyrosine kinase inhibitor approved for HCC and it has represented the standard of care for advanced HCC for almost 10 years, offering a survival benefit when compared to pla...

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Detalles Bibliográficos
Autores principales: Fornari, Francesca, Giovannini, Catia, Piscaglia, Fabio, Gramantieri, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260177/
https://www.ncbi.nlm.nih.gov/pubmed/34239844
http://dx.doi.org/10.2147/JHC.S285726