Citric Acid in Drug Formulations Causes Pain by Potentiating Acid-Sensing Ion Channel 1

Pain at the injection site is a common complaint of patients receiving therapeutic formulations containing citric acid. Despite the widely acknowledged role of acid-sensing ion channels (ASICs) in acid-related perception, the specific ASIC subtype mediating pain caused by subcutaneous acid injection...

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Detalles Bibliográficos
Autores principales: Yang, Ya Lan, Lai, Ted Weita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260239/
https://www.ncbi.nlm.nih.gov/pubmed/33888605
http://dx.doi.org/10.1523/JNEUROSCI.2087-20.2021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260239/
https://www.ncbi.nlm.nih.gov/pubmed/33888605
http://dx.doi.org/10.1523/JNEUROSCI.2087-20.2021

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