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Citric Acid in Drug Formulations Causes Pain by Potentiating Acid-Sensing Ion Channel 1
Pain at the injection site is a common complaint of patients receiving therapeutic formulations containing citric acid. Despite the widely acknowledged role of acid-sensing ion channels (ASICs) in acid-related perception, the specific ASIC subtype mediating pain caused by subcutaneous acid injection...
Autores principales: | Yang, Ya Lan, Lai, Ted Weita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260239/ https://www.ncbi.nlm.nih.gov/pubmed/33888605 http://dx.doi.org/10.1523/JNEUROSCI.2087-20.2021 |
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