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Incorporating Differential Gene Expression Analysis with Predictive Biomarkers to Identify Novel Therapeutic Drugs for Fuchs Endothelial Corneal Dystrophy

PURPOSE: Based on the differential gene expression analysis for predictive biomarkers with RNA-Sequencing data from Fuchs endothelial corneal dystrophy (FECD) patients, we are aiming to evaluate the efficacy of Library of Integrated Network-based Cellular Signatures (LINCS) perturbagen prediction so...

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Detalles Bibliográficos
Autores principales: Wen, Huaming, Gallo, Ryan A., Huang, Xiaosheng, Cai, Jiamin, Mei, Shaoyi, Farooqi, Ammad Ahmad, Zhao, Jun, Tao, Wensi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260298/
https://www.ncbi.nlm.nih.gov/pubmed/34258047
http://dx.doi.org/10.1155/2021/5580595