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miR-34c inhibits PDGF-BB-induced HAVSMCs phenotypic transformation and proliferation via PDGFR-β/SIRT1 pathway

The purpose of this study was to explore the effect of miR-34c on PDGF-BB-induced HAVSMCs phenotypic transformation and proliferation via PDGFR-β/SIRT1 pathway, so as to find a new method for early diagnosis and treatment of cardiovascular disease. HA-VSMCs were treated with platelet-derived growth...

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Detalles Bibliográficos
Autores principales: Wan, Wei-feng, Zhang, Xin, Huang, Chang-ren, Chen, Li-gang, Yang, Xiao-bo, Bao, Kun-yang, Peng, Tang-ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260521/
https://www.ncbi.nlm.nih.gov/pubmed/34110576
http://dx.doi.org/10.1007/s11033-021-06427-5