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Evolution of frustrated and stabilising contacts in reconstructed ancient proteins
Energetic properties of a protein are a major determinant of its evolutionary fitness. Using a reconstruction algorithm, dating the reconstructed proteins and calculating the interaction network between their amino acids through a coevolutionary approach, we studied how the interactions that stabili...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260555/ https://www.ncbi.nlm.nih.gov/pubmed/33569610 http://dx.doi.org/10.1007/s00249-021-01500-0 |