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GMP-compliant production of [(68)Ga]Ga-NeoB for positron emission tomography imaging of patients with gastrointestinal stromal tumor

BACKGROUND: [(68)Ga]Ga-NeoB is a novel DOTA-coupled Gastrin Releasing Peptide Receptor (GRPR) antagonist with high affinity for GRPR and good in vivo stability. This study aimed at (1) the translation of preclinical results to the clinics and establish the preparation of [(68)Ga]Ga-NeoB using a GMP...

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Detalles Bibliográficos
Autores principales: Pretze, Marc, Reffert, Laura, Diehl, Steffen, Schönberg, Stefan O., Wängler, Carmen, Hohenberger, Peter, Wängler, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260665/
https://www.ncbi.nlm.nih.gov/pubmed/34228236
http://dx.doi.org/10.1186/s41181-021-00137-w