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GMP-compliant production of [(68)Ga]Ga-NeoB for positron emission tomography imaging of patients with gastrointestinal stromal tumor
BACKGROUND: [(68)Ga]Ga-NeoB is a novel DOTA-coupled Gastrin Releasing Peptide Receptor (GRPR) antagonist with high affinity for GRPR and good in vivo stability. This study aimed at (1) the translation of preclinical results to the clinics and establish the preparation of [(68)Ga]Ga-NeoB using a GMP...
Autores principales: | Pretze, Marc, Reffert, Laura, Diehl, Steffen, Schönberg, Stefan O., Wängler, Carmen, Hohenberger, Peter, Wängler, Björn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260665/ https://www.ncbi.nlm.nih.gov/pubmed/34228236 http://dx.doi.org/10.1186/s41181-021-00137-w |
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