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A scDb-based trivalent bispecific antibody for T-cell-mediated killing of HER3-expressing cancer cells
HER3 is a member of the EGF receptor family and elevated expression is associated with cancer progression and therapy resistance. HER3-specific T-cell engagers might be a suitable treatment option to circumvent the limited efficacy observed for HER3-blocking antibodies in clinical trials. In this st...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260734/ https://www.ncbi.nlm.nih.gov/pubmed/34230555 http://dx.doi.org/10.1038/s41598-021-93351-0 |