An ARHGAP25 variant links aberrant Rac1 function to early‐onset skeletal fragility

Ras homologous guanosine triphosphatases (RhoGTPases) control several cellular functions, including cytoskeletal actin remodeling and cell migration. Their activities are downregulated by GTPase‐activating proteins (GAPs). Although RhoGTPases are implicated in bone remodeling and osteoclast and oste...

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Detalles Bibliográficos
Autores principales: Mäkitie, Riikka E., Henning, Petra, Jiu, Yaming, Kämpe, Anders, Kogan, Konstantin, Costantini, Alice, Välimäki, Ville‐Valtteri, Medina‐Gomez, Carolina, Pekkinen, Minna, Salusky, Isidro B., Schalin‐Jäntti, Camilla, Haanpää, Maria K., Rivadeneira, Fernando, Bassett, John H. Duncan, Williams, Graham R., Lerner, Ulf H., Pereira, Renata C., Lappalainen, Pekka, Mäkitie, Outi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260816/
https://www.ncbi.nlm.nih.gov/pubmed/34258505
http://dx.doi.org/10.1002/jbm4.10509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260816/
https://www.ncbi.nlm.nih.gov/pubmed/34258505
http://dx.doi.org/10.1002/jbm4.10509

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