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Defects in Macrophage Reprogramming in Cancer Therapy: The Negative Impact of PD-L1/PD-1

Classically activated M1 macrophages and alternatively activated M2 macrophages are two polarized subsets of macrophages at the extreme ends of a constructed continuum. In the field of cancer research, M2 macrophage reprogramming is defined as the repolarization of pro-tumoral M2 to anti-tumoral M1...

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Detalles Bibliográficos
Autores principales: Cai, Hao, Zhang, Yichi, Wang, Jian, Gu, Jinyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260839/
https://www.ncbi.nlm.nih.gov/pubmed/34248982
http://dx.doi.org/10.3389/fimmu.2021.690869