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Defects in Macrophage Reprogramming in Cancer Therapy: The Negative Impact of PD-L1/PD-1
Classically activated M1 macrophages and alternatively activated M2 macrophages are two polarized subsets of macrophages at the extreme ends of a constructed continuum. In the field of cancer research, M2 macrophage reprogramming is defined as the repolarization of pro-tumoral M2 to anti-tumoral M1...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260839/ https://www.ncbi.nlm.nih.gov/pubmed/34248982 http://dx.doi.org/10.3389/fimmu.2021.690869 |