A Novel Mutation in the NBD Domain of NLRC4 Causes Mild Autoinflammation With Recurrent Urticaria

BACKGROUND: NOD-like receptor family CARD-containing 4 protein (NLRC4) is a cytosolic protein that forms an inflammasome in response to flagellin and type 3 secretion system (T3SS) proteins from invading Gram-negative bacteria. NLRC4 mutations have been recently identified in early-onset severe auto...

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Detalles Bibliográficos
Autores principales: Wang, Li, Wen, Wen, Deng, Mengyue, Li, Yue, Sun, Gan, Zhao, Xiaodong, Tang, Xuemei, Mao, Huawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260849/
https://www.ncbi.nlm.nih.gov/pubmed/34248956
http://dx.doi.org/10.3389/fimmu.2021.674808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260849/
https://www.ncbi.nlm.nih.gov/pubmed/34248956
http://dx.doi.org/10.3389/fimmu.2021.674808

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