DNA polymerase λ promotes error-free replication through Watson–Crick impairing N1-methyl-deoxyadenosine adduct in conjunction with DNA polymerase ζ

In a previous study, we showed that replication through the N1-methyl-deoxyadenosine (1-MeA) adduct in human cells is mediated via three different Polι/Polθ, Polη, and Polζ-dependent pathways. Based on biochemical studies with these Pols, in the Polι/Polθ pathway, we inferred a role for Polι in the...

Descripción completa

Detalles Bibliográficos
Autores principales: Yoon, Jung-Hoon, Basu, Debashree, Choudhury, Jayati Roy, Prakash, Satya, Prakash, Louise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260881/
https://www.ncbi.nlm.nih.gov/pubmed/34119520
http://dx.doi.org/10.1016/j.jbc.2021.100868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260881/
https://www.ncbi.nlm.nih.gov/pubmed/34119520
http://dx.doi.org/10.1016/j.jbc.2021.100868

Ejemplares similares