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DNA polymerase λ promotes error-free replication through Watson–Crick impairing N1-methyl-deoxyadenosine adduct in conjunction with DNA polymerase ζ
In a previous study, we showed that replication through the N1-methyl-deoxyadenosine (1-MeA) adduct in human cells is mediated via three different Polι/Polθ, Polη, and Polζ-dependent pathways. Based on biochemical studies with these Pols, in the Polι/Polθ pathway, we inferred a role for Polι in the...
Autores principales: | Yoon, Jung-Hoon, Basu, Debashree, Choudhury, Jayati Roy, Prakash, Satya, Prakash, Louise |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260881/ https://www.ncbi.nlm.nih.gov/pubmed/34119520 http://dx.doi.org/10.1016/j.jbc.2021.100868 |
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