Caspase-11–Mediated Hepatocytic Pyroptosis Promotes the Progression of Nonalcoholic Steatohepatitis

BACKGROUND: Nonalcoholic steatohepatitis (NASH) is an inflammatory disease with severe outcomes. Hepatocyte death, including apoptosis, necrosis, and pyroptosis, has been implicated in pathophysiology of NASH. Pyroptosis is mediated by inflammasome activation pathways including caspase-1–mediated ca...

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Detalles Bibliográficos
Autores principales: Zhu, Yingwei, Zhao, Han, Lu, Jian, Lin, Kai, Ni, Jingbin, Wu, Gaojue, Tang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261017/
https://www.ncbi.nlm.nih.gov/pubmed/33894425
http://dx.doi.org/10.1016/j.jcmgh.2021.04.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261017/
https://www.ncbi.nlm.nih.gov/pubmed/33894425
http://dx.doi.org/10.1016/j.jcmgh.2021.04.009

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