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Imaging of type I procollagen biosynthesis in cells reveals biogenesis in highly organized bodies; Collagenosomes

Mechanistic aspects of type I procollagen biosynthesis in cells are poorly understood. To provide more insight into this process we designed a system to directly image type I procollagen biogenesis by co-expression of fluorescently labeled full size procollagen α1(I) and one α2(I) polypeptides. High...

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Detalles Bibliográficos
Autores principales: Stefanovic, Branko, Stefanovic, Lela, Manojlovic, Zarko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261018/
https://www.ncbi.nlm.nih.gov/pubmed/34278289
http://dx.doi.org/10.1016/j.mbplus.2021.100076