Small changes in the length of diselenide bond-containing linkages exert great influences on the antitumor activity of docetaxel homodimeric prodrug nanoassemblies

Homodimeric prodrug-based self-assembled nanoparticles, with carrier-free structure and ultrahigh drug loading, is drawing more and more attentions. Homodimeric prodrugs are composed of two drug molecules and a pivotal linkage. The influence of the linkages on the self-assembly, in vivo fate and ant...

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Detalles Bibliográficos
Autores principales: Li, Lingxiao, Zuo, Shiyi, Dong, Fudan, Liu, Tian, Gao, Yanlin, Yang, Yinxian, Wang, Xin, Sun, Jin, Sun, Bingjun, He, Zhonggui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2021
Materias:
Original Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261084/
https://www.ncbi.nlm.nih.gov/pubmed/34276822
http://dx.doi.org/10.1016/j.ajps.2021.02.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261084/
https://www.ncbi.nlm.nih.gov/pubmed/34276822
http://dx.doi.org/10.1016/j.ajps.2021.02.002

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