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Sex Steroids and Osteoarthritis: A Mendelian Randomization Study

OBJECTIVE: Sex steroids are thought to contribute to the pathogenesis of osteoarthritis (OA). This study investigated the causal role of sex steroids in site- and sex-specific OA and risk of joint replacement surgery using the Mendelian randomization (MR) method. METHODS: Instrumental variables for...

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Detalles Bibliográficos
Autores principales: Yan, Yi-Shang, Qu, Zihao, Yu, Dan-Qing, Wang, Wei, Yan, Shigui, Huang, He-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261132/
https://www.ncbi.nlm.nih.gov/pubmed/34248845
http://dx.doi.org/10.3389/fendo.2021.683226