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Endothelin-1 induces changes in the expression levels of steroidogenic enzymes and increases androgen receptor and testosterone production in the PC3 prostate cancer cell line

Endothelin-1 (ET-1) is involved in the regulation of steroidogenesis. Additionally, patients with castration-resistant prostate cancer (PCa) have a higher ET-1 plasma concentration than those with localized PCa and healthy individuals. The aim of the present study was to evaluate the effect of ET-1...

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Detalles Bibliográficos
Autores principales: Torres, María José, López-Moncada, Fernanda, Herrera, Daniela, Indo, Sebastián, Lefian, Alejandro, Llanos, Paola, Tapia, Julio, Castellón, Enrique A., Contreras, Héctor R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261198/
https://www.ncbi.nlm.nih.gov/pubmed/34165174
http://dx.doi.org/10.3892/or.2021.8122