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Endothelin-1 induces changes in the expression levels of steroidogenic enzymes and increases androgen receptor and testosterone production in the PC3 prostate cancer cell line
Endothelin-1 (ET-1) is involved in the regulation of steroidogenesis. Additionally, patients with castration-resistant prostate cancer (PCa) have a higher ET-1 plasma concentration than those with localized PCa and healthy individuals. The aim of the present study was to evaluate the effect of ET-1...
Autores principales: | Torres, María José, López-Moncada, Fernanda, Herrera, Daniela, Indo, Sebastián, Lefian, Alejandro, Llanos, Paola, Tapia, Julio, Castellón, Enrique A., Contreras, Héctor R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261198/ https://www.ncbi.nlm.nih.gov/pubmed/34165174 http://dx.doi.org/10.3892/or.2021.8122 |
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