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Murepavadin, a Small Molecule Host Defense Peptide Mimetic, Activates Mast Cells via MRGPRX2 and MrgprB2

Pseudomonas aeruginosa is a frequent cause of hospital-acquired wound infection and is difficult to treat because it forms biofilms and displays antibiotic resistance. Previous studies in mice demonstrated that mast cells (MCs) not only contribute to P. aeruginosa eradication but also promote wound...

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Detalles Bibliográficos
Autores principales: Amponnawarat, Aetas, Chompunud Na Ayudhya, Chalatip, Ali, Hydar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261236/
https://www.ncbi.nlm.nih.gov/pubmed/34248979
http://dx.doi.org/10.3389/fimmu.2021.689410