Circulating extracellular vesicles from patients with acute chest syndrome disrupt adherens junctions between endothelial cells

BACKGROUND: Small cell-derived extracellular vesicles (EVs) can affect endothelial function. We previously found that patients with sickle cell disease (SCD) have greater numbers of circulating EVs than subjects without the disease, and the EVs differentially disrupt endothelial integrity in vitro....

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Detalles Bibliográficos
Autores principales: Lapping-Carr, Gabrielle, Gemel, Joanna, Mao, Yifan, Sparks, Gianna, Harrington, Margaret, Peddinti, Radhika, Beyer, Eric C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261277/
https://www.ncbi.nlm.nih.gov/pubmed/32454519
http://dx.doi.org/10.1038/s41390-020-0923-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261277/
https://www.ncbi.nlm.nih.gov/pubmed/32454519
http://dx.doi.org/10.1038/s41390-020-0923-5

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