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Circulating extracellular vesicles from patients with acute chest syndrome disrupt adherens junctions between endothelial cells
BACKGROUND: Small cell-derived extracellular vesicles (EVs) can affect endothelial function. We previously found that patients with sickle cell disease (SCD) have greater numbers of circulating EVs than subjects without the disease, and the EVs differentially disrupt endothelial integrity in vitro....
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261277/ https://www.ncbi.nlm.nih.gov/pubmed/32454519 http://dx.doi.org/10.1038/s41390-020-0923-5 |