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Delivering Antisense Oligonucleotides across the Blood‐Brain Barrier by Tumor Cell‐Derived Small Apoptotic Bodies

The blood‐brain barrier (BBB) is the most restrictive and complicated barrier that keeps most biomolecules and drugs from the brain. An efficient brain delivery strategy is urgently needed for the treatment of brain diseases. Based on the studies of brain‐targeting extracellular vesicles (EVs), the...

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Detalles Bibliográficos
Autores principales: Wang, Yulian, Pang, Jiayun, Wang, Qingyun, Yan, Luocheng, Wang, Lintao, Xing, Zhen, Wang, Chunming, Zhang, Junfeng, Dong, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261483/
https://www.ncbi.nlm.nih.gov/pubmed/34258157
http://dx.doi.org/10.1002/advs.202004929