Synaptic disruption and CREB‐regulated transcription are restored by K(+) channel blockers in ALS

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease, which is still missing effective therapeutic strategies. Although manipulation of neuronal excitability has been tested in murine and human ALS models, it is still under debate whether neuronal activity might represent a valid...

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Detalles Bibliográficos
Autores principales: Catanese, Alberto, Rajkumar, Sandeep, Sommer, Daniel, Freisem, Dennis, Wirth, Alexander, Aly, Amr, Massa‐López, David, Olivieri, Andrea, Torelli, Federica, Ioannidis, Valentin, Lipecka, Joanna, Guerrera, Ida Chiara, Zytnicki, Daniel, Ludolph, Albert, Kabashi, Edor, Mulaw, Medhanie A, Roselli, Francesco, Böckers, Tobias M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261490/
https://www.ncbi.nlm.nih.gov/pubmed/34125498
http://dx.doi.org/10.15252/emmm.202013131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261490/
https://www.ncbi.nlm.nih.gov/pubmed/34125498
http://dx.doi.org/10.15252/emmm.202013131

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