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Ang2 inhibitors and Tie2 activators: potential therapeutics in perioperative treatment of early stage cancer

Anti‐angiogenic drugs targeting the VEGF pathway are most effective in advanced metastatic disease settings of certain types of cancers, whereas they have been unsuccessful as adjuvant therapies of micrometastatic disease in numerous phase III trials involving early‐stage (resectable) cancers. Newer...

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Detalles Bibliográficos
Autores principales: Khan, Kabir A, Wu, Florence TH, Cruz‐Munoz, William, Kerbel, Robert S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261516/
https://www.ncbi.nlm.nih.gov/pubmed/34125494
http://dx.doi.org/10.15252/emmm.201708253