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Pancreatic cancer intrinsic PI3Kα activity accelerates metastasis and rewires macrophage component

Pancreatic ductal adenocarcinoma (PDAC) patients frequently suffer from undetected micro‐metastatic disease. This clinical situation would greatly benefit from additional investigation. Therefore, we set out to identify key signalling events that drive metastatic evolution from the pancreas. We sear...

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Detalles Bibliográficos
Autores principales: Thibault, Benoit, Ramos‐Delgado, Fernanda, Pons‐Tostivint, Elvire, Therville, Nicole, Cintas, Celia, Arcucci, Silvia, Cassant‐Sourdy, Stephanie, Reyes‐Castellanos, Gabriela, Tosolini, Marie, Villard, Amelie V, Cayron, Coralie, Baer, Romain, Bertrand‐Michel, Justine, Pagan, Delphine, Ferreira Da Mota, Dina, Yan, Hongkai, Falcomatà, Chiara, Muscari, Fabrice, Bournet, Barbara, Delord, Jean‐Pierre, Aksoy, Ezra, Carrier, Alice, Cordelier, Pierre, Saur, Dieter, Basset, Celine, Guillermet‐Guibert, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261517/
https://www.ncbi.nlm.nih.gov/pubmed/34033220
http://dx.doi.org/10.15252/emmm.202013502