A pooled CRISPR/AsCpf1 screen using paired gRNAs to induce genomic deletions in Chinese hamster ovary cells

Chinese hamster ovary (CHO) cells are the most widely used host for the expression of therapeutic proteins. Recently, significant progress has been made due to advances in genome sequence and annotation quality to unravel the black box CHO. Nevertheless, in many cases the link between genotype and p...

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Detalles Bibliográficos
Autores principales: Schmieder, Valerie, Novak, Neža, Dhiman, Heena, Nguyen, Ly Ngoc, Serafimova, Evgenija, Klanert, Gerald, Baumann, Martina, Kildegaard, Helene Faustrup, Borth, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261548/
https://www.ncbi.nlm.nih.gov/pubmed/34277363
http://dx.doi.org/10.1016/j.btre.2021.e00649

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261548/
https://www.ncbi.nlm.nih.gov/pubmed/34277363
http://dx.doi.org/10.1016/j.btre.2021.e00649

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