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Rational design of a photoswitchable DNA glue enabling high regulatory function and supramolecular chirality transfer

Short, complementary DNA single strands with mismatched base pairs cannot undergo spontaneous formation of duplex DNA (dsDNA). Mismatch binding ligands (MBLs) can compensate this effect, inducing the formation of the double helix and thereby acting as a molecular glue. Here, we present the rational...

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Detalles Bibliográficos
Autores principales: Simeth, Nadja A., Kobayashi, Shotaro, Kobauri, Piermichele, Crespi, Stefano, Szymanski, Wiktor, Nakatani, Kazuhiko, Dohno, Chikara, Feringa, Ben L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261765/
https://www.ncbi.nlm.nih.gov/pubmed/34276952
http://dx.doi.org/10.1039/d1sc02194j