Phosphite mediated asymmetric N to C migration for the synthesis of chiral heterocycles from primary amines

A phosphite mediated stereoretentive C–H alkylation of N-alkylpyridinium salts derived from chiral primary amines was achieved. The reaction proceeds through the activation of the N-alkylpyridinium salt substrate with a nucleophilic phosphite catalyst, followed by a base mediated [1,2] aza-Wittig re...

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Detalles Bibliográficos
Autores principales: Rani, Soniya, Dash, Soumya Ranjan, Bera, Asish, Alam, Md Nirshad, Vanka, Kumar, Maity, Pradip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261767/
https://www.ncbi.nlm.nih.gov/pubmed/34276927
http://dx.doi.org/10.1039/d1sc01217g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261767/
https://www.ncbi.nlm.nih.gov/pubmed/34276927
http://dx.doi.org/10.1039/d1sc01217g

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