Co-delivery of novel bispecific and trispecific engagers by an amplicon vector augments the therapeutic effect of an HSV-based oncolytic virotherapy

BACKGROUND: Although oncolytic virotherapy has shown substantial promises as a new treatment modality for many malignancies, further improvement on its therapeutic efficacy will likely bring more clinical benefits. One plausible way of enhancing the therapeutic effect of virotherapy is to enable it...

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Detalles Bibliográficos
Autores principales: Ravirala, Divya, Mistretta, Brandon, Gunaratne, Preethi H, Pei, Guangsheng, Zhao, Zhongming, Zhang, Xiaoliu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Oncolytic and Local Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261877/
https://www.ncbi.nlm.nih.gov/pubmed/34230110
http://dx.doi.org/10.1136/jitc-2021-002454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261877/
https://www.ncbi.nlm.nih.gov/pubmed/34230110
http://dx.doi.org/10.1136/jitc-2021-002454

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