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Identification of novel genes involved in apoptosis of HIV-infected macrophages using unbiased genome-wide screening

BACKGROUND: Macrophages, besides resting latently infected CD4+ T cells, constitute the predominant stable, major non-T cell HIV reservoirs. Therefore, it is essential to eliminate both latently infected CD4+ T cells and tissue macrophages to completely eradicate HIV in patients. Until now, most of...

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Detalles Bibliográficos
Autores principales: Dong, Simon X. M., Vizeacoumar, Frederick S., Bhanumathy, Kalpana K., Alli, Nezeka, Gonzalez-Lopez, Cristina, Gajanayaka, Niranjala, Caballero, Ramon, Ali, Hamza, Freywald, Andrew, Cassol, Edana, Angel, Jonathan B., Vizeacoumar, Franco J., Kumar, Ashok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261936/
https://www.ncbi.nlm.nih.gov/pubmed/34233649
http://dx.doi.org/10.1186/s12879-021-06346-7