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Chronic colitis exacerbates NLRP3-dependent neuroinflammation and cognitive impairment in middle-aged brain

BACKGROUND: Neuroinflammation is a major driver of age-related brain degeneration and concomitant functional impairment. In patients with Alzheimer’s disease, the most common form of age-related dementia, factors that enhance neuroinflammation may exacerbate disease progression, in part by impairing...

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Detalles Bibliográficos
Autores principales: He, Xiao-fei, Li, Li-li, Xian, Wen-biao, Li, Ming-yue, Zhang, Li-ying, Xu, Jing-hui, Pei, Zhong, Zheng, Hai-qing, Hu, Xi-quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262017/
https://www.ncbi.nlm.nih.gov/pubmed/34229722
http://dx.doi.org/10.1186/s12974-021-02199-8