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Chronic colitis exacerbates NLRP3-dependent neuroinflammation and cognitive impairment in middle-aged brain
BACKGROUND: Neuroinflammation is a major driver of age-related brain degeneration and concomitant functional impairment. In patients with Alzheimer’s disease, the most common form of age-related dementia, factors that enhance neuroinflammation may exacerbate disease progression, in part by impairing...
Autores principales: | He, Xiao-fei, Li, Li-li, Xian, Wen-biao, Li, Ming-yue, Zhang, Li-ying, Xu, Jing-hui, Pei, Zhong, Zheng, Hai-qing, Hu, Xi-quan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262017/ https://www.ncbi.nlm.nih.gov/pubmed/34229722 http://dx.doi.org/10.1186/s12974-021-02199-8 |
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