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hTERT Transduction Extends the Lifespan of Primary Pediatric Low-Grade Glioma Cells While Preserving the Biological Response to NGF

The neurotrophin nerve growth factor (NGF) modulates the growth of human gliomas and is able to induce cell differentiation through the engagement of tropomyosin receptor kinase A (TrkA) receptor, although the role played in controlling glioma survival has proved controversial. Unfortunately, the sl...

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Detalles Bibliográficos
Autores principales: Franzese, Ornella, Di Francesco, Angela M., Meco, Daniela, Graziani, Grazia, Cusano, Gabriella, Levati, Lauretta, Riccardi, Riccardo, Ruggiero, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262147/
https://www.ncbi.nlm.nih.gov/pubmed/34257579
http://dx.doi.org/10.3389/pore.2021.612375