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Cell Cycle Regulatory Protein Expression in Multinucleated Giant Cells of Giant Cell Tumor of Bone: do They Proliferate?

Cells of the monocyte macrophage lineage form multinucleated giant cells (GCs) by fusion, which may express some cell cycle markers. By using a comprehensive marker set, here we looked for potential replication activities in GCs, and investigated whether these have diagnostic or clinical relevance i...

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Detalles Bibliográficos
Autores principales: Maros, Mate E., Balla, Peter, Micsik, Tamas, Sapi, Zoltan, Szendroi, Miklos, Wenz, Holger, Groden, Christoph, Forsyth, Ramses G., Picci, Piero, Krenacs, Tibor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262213/
https://www.ncbi.nlm.nih.gov/pubmed/34257609
http://dx.doi.org/10.3389/pore.2021.643146