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Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank

BACKGROUND: Epidemiological studies report increased comorbidity between depression and autoimmune diseases. The role of shared genetic influences in the observed comorbidity is unclear. We investigated the evidence for pleiotropy between these traits in the UK Biobank (UKB). METHODS: We defined aut...

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Detalles Bibliográficos
Autores principales: Glanville, Kylie P., Coleman, Jonathan R.I., O'Reilly, Paul F., Galloway, James, Lewis, Cathryn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262258/
https://www.ncbi.nlm.nih.gov/pubmed/34278373
http://dx.doi.org/10.1016/j.bpsgos.2021.03.002