TIGIT modulates sepsis-induced immune dysregulation in mice with preexisting malignancy

TIGIT is a recently identified coinhibitory receptor that is upregulated in the setting of cancer and functionally contributes to the impairment of antitumor immunity. However, its role during sepsis is unknown. Because patients with cancer are 10 times more likely to die of sepsis than previously h...

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Detalles Bibliográficos
Autores principales: Zhang, Wenxiao, Anyalebechi, Jerome C., Ramonell, Kimberly M., Chen, Ching-wen, Xie, Jianfeng, Liang, Zhe, Chihade, Deena B., Otani, Shunsuke, Coopersmith, Craig M., Ford, Mandy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262279/
https://www.ncbi.nlm.nih.gov/pubmed/34100383
http://dx.doi.org/10.1172/jci.insight.139823

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262279/
https://www.ncbi.nlm.nih.gov/pubmed/34100383
http://dx.doi.org/10.1172/jci.insight.139823

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