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LIN28B induces a differentiation program through CDX2 in colon cancer

Most colorectal cancers (CRCs) are moderately differentiated or well differentiated, a status that is preserved even in metastatic tumors. However, the molecular mechanisms underlying CRC differentiation remain to be elucidated. Herein, we unravel a potentially novel posttranscriptional regulatory m...

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Detalles Bibliográficos
Autores principales: Suzuki, Kensuke, Masuike, Yasunori, Mizuno, Rei, Sachdeva, Uma M., Chatterji, Priya, Andres, Sarah F., Sun, Wenping, Klein-Szanto, Andres J., Besharati, Sepideh, Remotti, Helen E., Verzi, Michael P., Rustgi, Anil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262288/
https://www.ncbi.nlm.nih.gov/pubmed/33755595
http://dx.doi.org/10.1172/jci.insight.140382