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Clinical application of intrathecal gadobutrol for assessment of cerebrospinal fluid tracer clearance to blood

BACKGROUND: Methodology for estimation of cerebrospinal fluid (CSF) tracer clearance could have wide clinical application in predicting excretion of intrathecal drugs and metabolic solutes from brain metabolism and for diagnostic workup of CSF disturbances. METHODS: The MRI contrast agent gadobutrol...

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Detalles Bibliográficos
Autores principales: Eide, Per K., Mariussen, Espen, Uggerud, Hilde, Pripp, Are H., Lashkarivand, Aslan, Hassel, Bjørnar, Christensen, Hege, Hovd, Markus Herberg, Ringstad, Geir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262318/
https://www.ncbi.nlm.nih.gov/pubmed/33822769
http://dx.doi.org/10.1172/jci.insight.147063