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Assessment of kidney proximal tubular secretion in critical illness

BACKGROUND: Serum creatinine concentrations (SCrs) are used to determine the presence and severity of acute kidney injury (AKI). SCr is primarily eliminated by glomerular filtration; however, most mechanisms of AKI in critical illness involve kidney proximal tubules, where tubular secretion occurs....

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Detalles Bibliográficos
Autores principales: Bhatraju, Pavan K., Chai, Xin-Ya, Sathe, Neha A., Ruzinski, John, Siew, Edward D., Himmelfarb, Jonathan, Hoofnagle, Andrew N., Wurfel, Mark M., Kestenbaum, Bryan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262320/
https://www.ncbi.nlm.nih.gov/pubmed/33886506
http://dx.doi.org/10.1172/jci.insight.145514