Antibody-mediated depletion of CCR10(+)EphA3(+) cells ameliorates fibrosis in IPF

Idiopathic pulmonary fibrosis (IPF) is characterized by aberrant repair that diminishes lung function via mechanisms that remain poorly understood. CC chemokine receptor (CCR10) and its ligand CCL28 were both elevated in IPF compared with normal donors. CCR10 was highly expressed by various cells fr...

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Detalles Bibliográficos
Autores principales: Hohmann, Miriam S., Habiel, David M., Espindola, Milena S., Huang, Guanling, Jones, Isabelle, Narayanan, Rohan, Coelho, Ana Lucia, Oldham, Justin M., Noth, Imre, Ma, Shwu-Fan, Kurkciyan, Adrianne, McQualter, Jonathan L., Carraro, Gianni, Stripp, Barry, Chen, Peter, Jiang, Dianhua, Noble, Paul W., Parks, William, Woronicz, John, Yarranton, Geoffrey, Murray, Lynne A., Hogaboam, Cory M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262321/
https://www.ncbi.nlm.nih.gov/pubmed/33945505
http://dx.doi.org/10.1172/jci.insight.141061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262321/
https://www.ncbi.nlm.nih.gov/pubmed/33945505
http://dx.doi.org/10.1172/jci.insight.141061

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