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The relationship between cytokine and neutrophil gene network distinguishes SARS-CoV-2–infected patients by sex and age

The fact that the COVID-19 fatality rate varies by sex and age is poorly understood. Notably, the outcome of SARS-CoV-2 infections mostly depends on the control of cytokine storm and the increasingly recognized pathological role of uncontrolled neutrophil activation. Here, we used an integrative app...

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Detalles Bibliográficos
Autores principales: Freire, Paula P., Marques, Alexandre H.C., Baiocchi, Gabriela C., Schimke, Lena F., Fonseca, Dennyson L.M., Salgado, Ranieri C., Filgueiras, Igor S., Napoleao, Sarah M.S., Plaça, Desirée R., Akashi, Karen T., Hirata, Thiago Dominguez Crespo, El Khawanky, Nadia, Giil, Lasse M., Cabral-Miranda, Gustavo, Carvalho, Robson F., Ferreira, Luis Carlos S., Condino-Neto, Antonio, Nakaya, Helder I., Jurisica, Igor, Ochs, Hans D., Camara, Niels Olsen Saraiva, Calich, Vera Lúcia G., Cabral-Marques, Otavio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262322/
https://www.ncbi.nlm.nih.gov/pubmed/34027897
http://dx.doi.org/10.1172/jci.insight.147535