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Striatal TRPV1 activation by acetaminophen ameliorates dopamine D(2) receptor antagonist–induced orofacial dyskinesia

Antipsychotics often cause tardive dyskinesia, an adverse symptom of involuntary hyperkinetic movements. Analysis of the US Food and Drug Administration Adverse Event Reporting System and JMDC insurance claims revealed that acetaminophen prevented the dyskinesia induced by dopamine D(2) receptor ant...

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Detalles Bibliográficos
Autores principales: Nagaoka, Koki, Nagashima, Takuya, Asaoka, Nozomi, Yamamoto, Hiroki, Toda, Chihiro, Kayanuma, Gen, Siswanto, Soni, Funahashi, Yasuhiro, Kuroda, Keisuke, Kaibuchi, Kozo, Mori, Yasuo, Nagayasu, Kazuki, Shirakawa, Hisashi, Kaneko, Shuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262333/
https://www.ncbi.nlm.nih.gov/pubmed/33857021
http://dx.doi.org/10.1172/jci.insight.145632