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A surgical method for continuous intraportal infusion of gut microbial metabolites in mice

Gut microbe–derived metabolites influence human physiology and disease. However, establishing mechanistic links between gut microbial metabolites and disease pathogenesis in animal models remains challenging. The major route of absorption for microbe-derived small molecules is venous drainage via th...

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Detalles Bibliográficos
Autores principales: Orabi, Danny, Osborn, Lucas J., Fung, Kevin, Massey, William, Horak, Anthony J., Aucejo, Federico, Choucair, Ibrahim, DeLucia, Beckey, Wang, Zeneng, Claesen, Jan, Brown, J. Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262340/
https://www.ncbi.nlm.nih.gov/pubmed/33986195
http://dx.doi.org/10.1172/jci.insight.145607